Episode 2: Other COVID-19 Vaccine Platforms
- Heather McSharry, PhD
- Apr 7
- 1 min read
Updated: Apr 8

This is the original Pathogen Perspectives episode rebranded for Infectious Dose.
In this episode, Heather provides an in-depth discussion on the COVID-19 vaccine platforms other than mRNA, currently in clinical trials around the world. These include self-replicating mRNA, DNA, Protein-based, Attenuated virus, Inactivated virus, Repurposed vaccines, and virus vector vaccines. Heather discusses what each platform is, their pros and cons, and let's you know about those with current emergency use authorization.
· What each platform involves
· Pros and cons
· Those of each type currently authorized for emergency use
· Unexpected introduction to salty Heather after a rough week.

Relevant links
Merck's HIV vaccine flop brings vectors under closer scrutiny. Ledford H. Nat Biotechnol. 2008 Jan;26(1):3-4. Behind paywall so here you go:
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